Opto 22 Headquarters
43044 Business Park Drive
Temecula, CA
92590-3614
Phone: 951-695-3000
Toll Free (in the U.S.): 800-321-6786

Opto 22 headquarters are located in Temecula, California. San Diego is about an hour to the south, and Los Angeles is about two hours to the northwest.
See accommodations near Opto 22. 

For air travel: 
San Diego International Airport
Ontario International Airport
Los Angeles International Airport
Palm Springs International Airport
John Wayne Airport, Orange County